BackgroundAlthough digital health is essential for improving health care, its adoption remains slow due to the lack of literacy in this area.Therefore, it is crucial for health professionals to acquire digital skills and for a digital competence assessment and accreditation model to be implemented to make advances in this field.ObjectiveThis study

The ubiquitin-like protein NEDD8/Rub1 is initially translated as a precursor and undergoes maturation before becoming functional, a process mediated by the ubiquitin hydrolase UCHL3/Yuh1.Across studied organisms, the mature form of NEDD8/Rub1 modifies cullins, the central subunits of CRLs.NEDD8/Rub1 modification typically enhances CRL-mediated ubiq

Nowadays, the use of metal processing additive technologies is a rapidly growing field in the manufacturing industry.These technologies, such as metal 3D printing (also known as additive manufacturing) and laser cladding, allow for the production of complex geometries and intricate designs that would be impossible with traditional manufacturing met

Summary: Gut motility is regulated by the microbiome via mechanisms that include bile acid metabolism.To localize the effects of microbiome-generated bile acids, we colonized gnotobiotic mice with different synthetic gut bacterial communities that were metabolically phenotyped using a functional in vitro screen.Using two Hockey Protective - Pants -

Abstract Background Human cerebral organoids (hCO) are attractive systems due to their ability to model important Carvin skimmer parts brain regions and transcriptomics of early in vivo brain development.To date, they have been used to understand the effects of genetics and soluble factors on neurodevelopment.Interestingly, one of the main advantag